nicotinamide

[ nik-uh-tin-uh-mahyd, -mid, -tee-nuh- ]

noun

, Biochemistry.

1. a colorless, crystalline, water-soluble solid, C 6 H 6 N 2 O, the amide of nicotinic acid, and a component of the vitamin-B complex, found in meat, liver, fish, whole wheat, and eggs: used in medicine chiefly as an agent for preventing or treating human pellagra or animal black tongue.

nicotinamide

/ ˌnɪkəˈtɪnəˌmaɪd; -ˈtiːn- /

noun

1. the amide of nicotinic acid: a component of the vitamin B complex and essential in the diet for the prevention of pellagra. Formula: C 6 H 6 ON 2

Word History and Origins

Origin of nicotinamide¹

First recorded in 1890–95; nicotine + amide

Example Sentences

The over-the-counter supplement nicotinamide riboside, a form of vitamin B3, increased the walking endurance of patients with peripheral artery disease, a chronic leg condition for which there are few effective treatments.

From Science Daily

"This is a signal that nicotinamide riboside could help these patients," said Christiaan Leeuwenburgh, Ph.D., a UF professor of physiology and aging and senior author of the clinical trial report.

From Science Daily

The scientists recruited 90 people with an average age of 71 who had peripheral artery disease, or PAD, to test the effects of nicotinamide riboside.

From Science Daily

Nicotinamide riboside is a precursor for the essential compound NAD, which plays roles in the body related to energy generation, improved blood flow and DNA repair.

From Science Daily

Because PAD is associated with problems generating energy within muscle cells, McDermott and Leeuwenburgh thought that nicotinamide riboside, by improving energy generation, could help improve walking in people with the disease.

From Science Daily