nicotinamide

American  

[nik-uh-tin-uh-mahyd, -mid, -tee-nuh-] / ˌnɪk əˈtɪn əˌmaɪd, -mɪd, -ˈti nə- /

noun

Biochemistry.

1. a colorless, crystalline, water-soluble solid, C 6 H 6 N 2 O, the amide of nicotinic acid, and a component of the vitamin-B complex, found in meat, liver, fish, whole wheat, and eggs: used in medicine chiefly as an agent for preventing or treating human pellagra or animal black tongue.

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nicotinamide British  

/ ˌnɪkəˈtɪnəˌmaɪd, -ˈtiːn- /

noun

1. the amide of nicotinic acid: a component of the vitamin B complex and essential in the diet for the prevention of pellagra. Formula: C 6 H 6 ON 2

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Etymology

Origin of nicotinamide

First recorded in 1890–95; nicotine + amide

Example Sentences

Because nicotinamide is available over the counter, its use is rarely documented in medical records.

From Science Daily • Oct. 20, 2025

NMNAT2 is a vital provider of nicotinamide adenine dinucleotide for the brain.

From Science Daily • Jan. 31, 2024

In September 2015, Diaz added two newer ones to intensify his treatment - dolutegravir and maraviroc - plus nicotinamide, a form of vitamin B3 that may help expose dormant virus.

From Washington Times • Jul. 7, 2020

On top of this “intensification,” the study group received nicotinamide, which can, in theory, prod infected cells to “wake up” the latent virus.

From Science Magazine • Jul. 7, 2020

These electrons are in a high-energy state and are transported to NAD+, also known as nicotinamide adenine dinucleotide.

From Textbooks • Jan. 1, 2018