amide

[ am-ahyd, -id ]

noun

, Chemistry.

1. a metallic derivative of ammonia in which the −NH 2 group is retained, as potassium amide, KNH 2 .
2. an organic compound obtained by replacing the −OH group in acids by the −NH 2 group.
3. an organic compound formed from ammonia by replacing a hydrogen atom by an acyl group.

amide

/ ˈæmaɪd; əˈmɪdɪk /

noun

1. any organic compound containing the functional group -CONH 2
2. modifier consisting of, containing, or concerned with the group -CONH 2

   amide group or radical

3. an inorganic compound having the general formula M(NH 2 ) x , where M is a metal atom

amide

/ ăm′īd′ /

1. Any organic compound containing the group CONH 2 , derived from a fatty acid by replacing the hydroxyl group (OH) of the carboxyl group (COOH) with an amino group (NH 2 ). Amides are volatile solids.

Derived Forms

• amidic, adjective

Other Words From

• a·mid·ic [uh, -, mid, -ik], adjective

Word History and Origins

Origin of amide¹

First recorded in 1840–50; am(monia) + -ide ( def )

Word History and Origins

Origin of amide¹

C19: from am ( monia ) + -ide

Example Sentences

The rotational properties were enabled by adding molecular components that contained an atom from the 'chalcogen' group of elements in the periodic table, specifically sulfur or selenium, to a simple organic molecule: an amide compound.

From Science Daily

When they gave one set of these molecules, fatty acid amides, to mice whose gut microbes had been wiped out with antibiotics, dopamine levels surged in the animals’ brains as they exercised.

From Science Magazine

The RNC and the Trump reelection campaign launched a joint multimillion-dollar legal campaign to block attempts by Democrats to change voting rules in states across the country amide the coronavirus pandemic.

From Fox News

The carbamoyl fluoride already contains the carbon–nitrogen bond of the target amide, thereby sidestepping the usual difficulties associated with making fluorinated amides.

From Nature

The very feature of the amide that makes it resistant to hydrolysis — the fact that it behaves in part like a double bond — also constrains it to a planar geometry.

From Nature