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indomethacin

American  
[in-doh-meth-uh-sin] / ˌɪn doʊˈmɛθ ə sɪn /

noun

Pharmacology.
  1. a substance, C 19 H 16 ClNO 4 , with anti-inflammatory, antipyretic, and analgesic properties: used in the treatment of certain kinds of arthritis and gout.


indomethacin British  
/ ˌɪndəʊˈmɛθəsɪn /

noun

  1. a drug administered orally to relieve pain, fever, and inflammation, esp in rheumatoid arthritis. Formula: C 19 H 16 ClNO 4

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of indomethacin

First recorded in 1963; indo(le) + meth(yl) + ac(etic) + -in 2

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Participants found ketorolac helpful 62% of the time, indomethacin was helpful 57% of the time, and diclofenac was helpful 56% of the time.

From Science Daily • Nov. 29, 2023

Researchers were quick to argue that this class-wide ban would cover substances that already exist as medicines, such as the anti-inflammatory drug indomethacin.

From Scientific American • Jan. 5, 2022

Gervais, whose test was negative, said she was elated to receive a provisional diagnosis and even happier shortly after starting a potent anti-inflammatory drug called indomethacin.

From Washington Post • Nov. 12, 2021

Researchers also found the risk of heart failure doubled for diclofenac, etoricoxib, indomethacin, piroxicam, and rofecoxib used at very high doses, although they stressed this should be interpreted with caution.

From The Guardian • Sep. 28, 2016

Researchers who compared the steroid prednisolone with the arthritis medication indomethacin found both drugs offered a similar degree of pain reduction.

From US News • Feb. 23, 2016