indole

[ in-dohl ]

noun

, Chemistry.

1. a colorless to yellowish solid, C 8 H 7 N, having a low melting point and a fecal odor, found in the oil of jasmine and clove and as a putrefaction product from animals' intestines: used in perfumery and as a reagent.

indole

/ ˈɪndəʊl; -dɒl; ˈɪndəʊl /

noun

1. a white or yellowish crystalline heterocyclic compound extracted from coal tar and used in perfumery, medicine, and as a flavouring agent; 1-benzopyrrole. Formula: C 8 H 7 N

indole

/ ĭn′dōl′ /

1. A white crystalline compound obtained from coal tar or various plants and produced by the bacterial decomposition of tryptophan in the intestine. It is used in the perfume industry and as a reagent. Chemical formula: C 8 H 7 N.
2. Any of various derivatives of this compound.

Word History and Origins

Origin of indole¹

First recorded in 1865–70; ind- + -ole ²

Word History and Origins

Origin of indole¹

C19: from ind ( igo ) + -ole ¹

Example Sentences

The paper concludes that "blockade of indole generation may present a unique therapeutic pathway" for rheumatoid arthritis and spondyloarthritis.

From Science Daily

"We put mice on antibiotics to wipe out their microbiome, and they didn't get arthritis, and they didn't have indole," she says.

From Science Daily

"So we said, OK, what if they do have a microbiome and we put them on a diet with little tryptophan? The microbiome can't break down tryptophan into indole, and the mice didn't get arthritis. So two different ways, we showed that it's tryptophan that's broken down by the microbiome into indole."

From Science Daily

"We found that when indole is present, the mice start to develop autoreactive T-cells that are more inflammatory. They have less of those regulatory T-cells that help maintain balance in the immune system, and they start to develop antibodies that are more pathogenic. We found that the antibodies had flags for being more inflammatory when indole was present."

From Science Daily

First, Herzon and his team avoided constructing a reactive heterocyclic ring, known as an indole, until the end of the process.

From Science Daily