cyclophosphamide

[ sahy-kluh-fos-fuh-mahyd, -mid, sik-luh- ]

noun

, Pharmacology.

1. a synthetic, crystalline, toxic substance, C 7 H 15 Cl 2 N 2 O 2 P, related to nitrogen mustard, used in the treatment of Hodgkin's disease, lymphoma, and certain leukemias. : CYC

cyclophosphamide

/ ˌsaɪkləʊˈfɒsfəˌmaɪd /

noun

1. an alkylating agent used in the treatment of leukaemia and lymphomas

Word History and Origins

Origin of cyclophosphamide¹

First recorded in 1955–60; cyclo- + phosph- + amide

Word History and Origins

Origin of cyclophosphamide¹

C20: from cyclo- + phosph ( orus ) + amide

Example Sentences

Nice said the drug cost £4,320 for a 1,800mg per 15ml vial and, along with bortezomib, cyclophosphamide and dexamethasone, was recommended as an option for treating newly diagnosed AL amyloidosis in adults.

From BBC

A component of the chemotherapy, cyclophosphamide, also suppresses regulatory T cells, which inhibit killer T cell responses.

From Science Daily

In two key papers in 2008 and 2012, his team reported that reducing nutrients in the medium used to grow cells in a dish protected normal cells from the toxic effects of chemotherapy drugs such as cyclophosphamide and doxorubicin, yet made cancer cells more likely to die.

From Science Magazine

I’d call it Cyclophosphamide, doxorubicin, paclitaxel, docetaxel, carboplatin, steroids, anti-inflammatories, antipsychotic antinausea meds, anti-anxiety anti-nausea meds, anti-nausea meds, antidepressants, sedatives, saline flushes, acid reducers, eyedrops, eardrops, numbing creams, alcohol wipes, blood thinners, antihistamines, antibiotics, antifungals, antibacterials, sleep aids, D3, B12, B6, joints and oils and edibles, hydrocodone, oxycodone, fentanyl, morphine, eyebrow pencils, face creams.

From The Guardian

One of the chemotherapy drugs with which I was treated, cyclophosphamide, passes into the urine only partially diluted, is only partially removed by water treatment methods, and lasts in the common water supply for 400 to 800 days.

From The Guardian