histamine

[ his-tuh-meen, -min ]

noun

1. Biochemistry, Physiology. a heterocyclic amine, C 5 H 9 N 3 , released by mast cells when tissue is injured or in allergic and inflammatory reactions, causing dilation of small blood vessels and smooth muscle contraction.
2. Pharmacology. a commercial form of this compound, obtained from histidine and used chiefly in the diagnosis of gastric and circulatory functions.

histamine

/ -mɪn; ˈhɪstəˌmiːn; ˌhɪstəˈmɪnɪk /

noun

1. an amine formed from histidine and released by the body tissues in allergic reactions, causing irritation. It also stimulates gastric secretions, dilates blood vessels, and contracts smooth muscle. Formula: C 5 H 9 N 3 See also antihistamine

histamine

/ hĭs′tə-mēn′ /

1. An organic compound found widely in animals and plants that in humans and other mammals is released as part of the body's immune response, causing physiological changes including dilation of the blood vessels, contraction of smooth muscle (as in the airways), and increased gastric acid secretion. The itching and sneezing typical of respiratory allergies are caused by the release of histamine. Chemical formula: C 5 H 9 N 3

Derived Forms

• histaminic, adjective

Other Words From

• his·ta·min·ic [his-t, uh, -, min, -ik], adjective

Word History and Origins

Origin of histamine¹

First recorded in 1910–15; hist(idine) + -amine

Word History and Origins

Origin of histamine¹

C20: from hist ( idine ) + -amine

Example Sentences

The acid-reducing drugs includeproton pump inhibitors such as omeprazole and esomeprazole, histamine H2-receptor antagonists, or H2 blockers, such as cimetidine and famotidine, and antacid supplements.

From Science Daily

These white blood cells are loaded with small sacs called "granules," which are full of enzymes and signaling molecules like histamine.

From Science Daily

These substances interact with EP3 receptors in MCs and prevent degranulation, limiting the release of histamine and minimizing allergic response.

From Science Daily

Histamine, a familiar name to allergy sufferers, emerges as a prominent figure in this narrative.

From Salon

Present in abundance, particularly in red wines, histamine can be the instigator of headaches, flushing, nasal symptoms, gut disturbances or even asthma.

From Salon