histidine

American  

[his-ti-deen, -din] / ˈhɪs tɪˌdin, -dɪn /

Also histidin

noun

Biochemistry.

1. an essential amino acid, C 3 H 3 N 2 CH 2 CH(NH2 )COOH, that is a constituent of proteins and is important as the iron-binding site in hemoglobin. His; H

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histidine British  

/ ˈhɪstɪˌdiːn, -dɪn /

noun

1. a nonessential amino acid that occurs in most proteins: a precursor of histamine

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histidine Scientific  

/ hĭs′tĭ-dēn′ /

1. An amino acid that is essential for children but not for adults. Chemical formula: C ₆ H ₉ N ₃ O ₂ .

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Etymology

Origin of histidine

First recorded in 1895–1900; hist- + -id ³ + -ine ²

Example Sentences

The sequencing data revealed a variant that substituted an amino acid called histidine for arginine.

From Scientific American

Me-His is an analogue of histidine in which a methyl group is attached to one of the nitrogen atoms in the side chain.

From Nature

Most actin isoforms are also methylated at a particular histidine amino-acid residue known as His73, which is close to the site to which one of two nucleotides, ATP or ADP, binds.

From Nature

Kanarek et al.1 report that, in mouse models and human cell lines, the sensitivity of cancer cells to methotrexate can be boosted by the metabolic degradation of the amino acid histidine.

From Nature

That survey yielded a gene that encodes an enzyme involved in synthesizing histidine.

From Nature