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Warburg
[ vahr-boork; English wawr-burg ]
noun
- Ot·to Hein·rich [awt, -oh , hahyn, -, r, i, kh], 1883–1970, German physiologist: Nobel Prize in medicine 1931.
Warburg
/ ˈvɑrbʊrk /
noun
- WarburgOtto (Heinrich)18831970MGermanSCIENCE: chemistSCIENCE: physiologist Otto ( Heinrich ) (ˈoto). 1883–1970, German biochemist and physiologist: Nobel prize for physiology or medicine (1931) for his work on respiratory enzymes
Example Sentences
The study, published as a Reviewed Preprint in eLife and now appearing as the final version, was described by the editors as providing convincing evidence that an intracellular subpopulation of a specific potassium channel reprograms breast cancer cells towards the Warburg phenotype, one of the metabolic hallmarks of cancer.
Cancer cells show increased energy demands due to their high growth rates and can switch their metabolism from a process requiring oxygen to one that allows them to grow in oxygen and nutrient-poor environments -- known as the Warburg effect.
Having found that BKCa helps cancer cells with reprogramming their metabolism, Dr. Bischof, first author of the study, specifically looked for evidence of the Warburg effect by measuring lactate concentrations over time; higher levels of lactate secretion imply a shift towards metabolism that does not use oxygen.
Hakstol and Ruff hail from the same small Alberta farming village of Warburg, population 766.
Hakstol hails from the tiny village of Warburg, Alberta.
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