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spironolactone

[ spahy-ruh-noh-lak-tohn, spahy-roh-, -ron-uh- ]

noun

, Pharmacology.
  1. a steroid, C 2 4 H 3 2 O 4 S, used in combination with other drugs as a diuretic and antihypertensive.


spironolactone

/ ˌspaɪrənəʊˈlæktəʊn /

noun

  1. a diuretic that increases water loss from the kidneys and is much used to treat oedema in heart and kidney failure
“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012


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Word History and Origins

Origin of spironolactone1

1955–60; alteration of spirolactone; spiro- 2, lactone
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Word History and Origins

Origin of spironolactone1

C20: from spiro- ² + linking syllable -no- + lactone
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Example Sentences

I also take several pills each morning to maintain the proper hormonal balance in my body: spironolactone to suppress testosterone and estradiol to increase estrogen.

From Salon

A toxicology analysis turned up positive for the diuretic spironolactone — commonly known by its brand name, Aldactone — and metformin, a diabetes medication that bodybuilders use for weight loss.

Other oral prescription medications have been used to treat hair loss over the past 10 to 20 years: spironolactone, finasteride and dutasteride.

So some dermatologists, including Dr. Sinclair, have added another drug — very low doses of spironolactone, a blood pressure drug that also blocks certain sex hormones called androgens — to try to prevent unwanted hair growth.

Food and Drug Administration to treat primary aldosteronism, spironolactone, was developed in the late 1950s.

From Salon

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