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ribozyme

[ rahy-buh-zahym ]

noun

  1. a segment of RNA that can act as a catalyst.


ribozyme

/ ˈraɪbəʊˌzaɪm /

noun

  1. an RNA molecule capable of catalysing a chemical reaction, usually the cleavage of another RNA molecule
“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Other Words From

  • ribo·zymal adjective
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Word History and Origins

Origin of ribozyme1

First recorded in 1985–90; ribo(some) + (en)zyme
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Word History and Origins

Origin of ribozyme1

C20: from ribo ( nucleic acid ) + ( en ) zyme
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Example Sentences

For this, they designed an artificial ribozyme, R3C ligase, to investigate how individual RNA units come together to form a functional structure.

Giving further insight into their work published on 17 April 2024, in Life, Prof. Tamura states, "The R3C ligase is a ribozyme that catalyzes the formation of a 3',5'-phosphodiester linkage between two RNA molecules. We modified the structure by adding specific domains that can interact with various effectors."

These findings suggest that ATP and histidine act as effector molecules that trigger structural conformational changes in the ribozyme, which further influence enzyme stability and activity.

As a result of this new research, these complex ribozyme sequences in the early stages of RNA evolution are not necessary.

The latest RNA polymerase ribozyme developed in the lab includes a number of crucial mutations that allow it to copy a strand of RNA with much higher accuracy.

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