phosphorylation

/ ˌfɒsfərɪˈleɪʃən /

noun

1. the chemical or enzymic introduction into a compound of a phosphoryl group (a trivalent radical of phosphorus and oxygen)

phosphorylation

/ fŏs′fər-ə-lā′shən /

1. The addition of a phosphate group to an organic molecule. Phosphorylation is important for many processes in living cells. ATP is formed during cell respiration from ADP by phosphorylation, as in the mitochondria of eukaryotic cells (oxidative phosphorylation) and the chloroplasts of plant cells (photosynthetic phosphorylation). Phosphorylation also regulates the activity of proteins, such as enzymes, which are often activated by the addition of a phosphate group and deactivated by its removal (called dephosphorylation ).

Example Sentences

Hisner notes that early on in the pandemic a common mutation that turned up in many variants right at or around the usually-highly phosphorylated N3 region of the nucleocapsid likewise decreased phosphorylation — just like the mutation that produced N* — and that this also appeared to produce more severe disease.

From Salon

Clearly, reducing the phosphorylation of N and creating N* has offered benefits that have allowed this mutation to flourish among generations of variants.

From Salon

Ghosh said the conflict stems from problematic phosphorylation, the attachment of a phosphate group to the G protein molecule.

From Science Daily

They found that these actions can all be traced back to metabolic dysregulation in a process within the B cells called oxidative phosphorylation, a type of mitochondrial respiration.

From Science Daily

"Even though the liver is not directly involved in exercise, it still undergoes changes that could improve health. No one speculated that we'd see these acetylation and phosphorylation changes in the liver after exercise training," said Jean-Beltran.

From Science Daily