Parkinson's disease

or Parkinson disease

noun

, Pathology.

1. a common neurologic disease believed to be caused by deterioration of the brain cells that produce dopamine, occurring primarily after the age of 60, characterized by tremors, especially of the fingers and hands, muscle rigidity, shuffling gait, slow speech, and a masklike facial expression.

Parkinson's disease

/ ˈpɑːkɪnsənz /

noun

1. a progressive chronic disorder of the central nervous system characterized by impaired muscular coordination and tremor Often shortened toParkinson's Also calledParkinsonismParkinson's syndromeparalysis agitansshaking palsy

Parkinson's disease

/ pär′kĭn-sənz /

1. A progressive neurologic disease occurring most often after the age of 50, associated with the destruction of brain cells that produce dopamine. Individuals with Parkinson's disease exhibit tremors while at rest, slowing of movement, stiffening of gait and posture, and weakness. The disease is named after its discoverer, British physician and paleontologist James Parkinson (1755–1824).

Parkinson's disease

1. A chronic disease of the nervous system that usually strikes in late adult life, resulting in a gradual decrease in muscle control. Symptoms of the disease include shaking, weakness, and partial paralysis of the face. Certain drugs can help alleviate some of its symptoms.

Word History and Origins

Origin of Parkinson's disease¹

Named after James Parkinson (1755–1824), English physician who first described it

Word History and Origins

Origin of Parkinson's disease¹

C19: named after James Parkinson (1755–1824), British surgeon, who first described it

Example Sentences

"In Parkinson's disease, when they're constantly activated, microglia can propagate further damage to the surrounding tissue. That's what we see in Parkinson's brains, particularly in regions associated with cognitive decline."

From Science Daily

A recently published study by researchers at the University of Arizona Health Sciences found that a tiny protein called PNA5 appears to have a protective effect on brain cells, which could lead to treatments for the cognitive symptoms of Parkinson's disease and related disorders.

From Science Daily

Parkinson's disease, a neurological disorder best known for causing tremors, stiffness, slow movement and poor balance, also causes cognitive symptoms that can progress to Parkinson's dementia.

From Science Daily

"When patients are diagnosed with Parkinson's disease, 25% to 30% already have mild cognitive impairment. As the disorder progresses into its later stages, 50% to 70% of patients complain of cognitive problems," said Lalitha Madhavan, MD, PhD, an associate professor of neurology at the University of Arizona College of Medicine -- Tucson.

From Science Daily

"The sad part is we don't have a clear way to treat cognitive decline or dementia in Parkinson's disease."

From Science Daily