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Paget's disease

noun

  1. Pathology. a chronic disease characterized by episodic accelerated bone resorption and growth of abnormal replacement bone, causing bone pain, deformation, fractures, and osteosarcoma; osteitis deformans.


Paget's disease

/ ˈpædʒɪts /

noun

  1. Also calledosteitis deformans a chronic disease of the bones characterized by inflammation and deformation
  2. Also calledPaget's cancer cancer of the nipple and surrounding tissue
“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012


Paget's disease

/ păjĭts /

  1. A disease, occurring chiefly in the elderly, in which the bones become enlarged and weakened, often resulting in fracture or deformity.
  2. A breast cancer manifested by inflammatory changes of the nipple and surrounding skin.


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Word History and Origins

Origin of Paget's disease1

1875–80; named after Sir James Paget, who described it
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Word History and Origins

Origin of Paget's disease1

C19: named after Sir James Paget (1814–99), British surgeon and pathologist, who described these diseases
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Example Sentences

Begg and his colleagues scanned the composer’s genome for several conditions linked to hearing loss, including Paget’s disease and lupus.

Some diseases include such as osteoma, rickets, low bone density and osteoporosis, osteomalacia, Paget’s disease of bone, bone and/or joint pain, osteogenesis imperfecta, increased frequency of fractures, deformed bones, chondrodystrophia fetalis, and other bone diseases that are caused by poor nutrition, genetics, or problems with the rate of bone growth.

Although grateful to be cancer-free, Mr. Riddick has additional health problems, including arthritis and Paget’s disease, which causes bone and joint pain.

The 69-year-old, from Knebworth, in Hertfordshire, has Paget's disease, which causes him severe pain and means he has to walk with a stick.

From BBC

They recommended that the drugs should only be authorized for short-term use in Paget's disease, a bone disorder; for acute bone loss due to sudden immobilization; and for excess calcium in the blood caused by cancer.

From Reuters

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