osteogenesis imperfecta

[ im-per-fek-tuh ]

noun

, Pathology.

1. a rare hereditary disease in which abnormal connective tissue development leads to fragile bones subject to fracture.

osteogenesis imperfecta

/ ˌɪmpəˈfɛktə /

noun

1. a hereditary disease caused by a collagen abnormality, causing fragility of the skeleton which results in fractures and deformities Also calledbrittle bone syndrome

osteogenesis imperfecta

/ ŏs′tē-ə-jĕn′ĭ-sĭsĭm′pər-fĕk′tə /

1. A hereditary disease characterized by abnormally brittle, easily fractured bones.

Word History and Origins

Origin of osteogenesis imperfecta¹

1900–05; < New Latin: imperfect osteogenesis

Example Sentences

Due to her condition, osteogenesis imperfecta - which creates brittle bones - Ms Watkins said gaining proper healthcare is almost impossible.

From BBC

And will understanding this mechanism offer insights into conditions where something is wrong with collagen, such as osteogenesis imperfecta?

From Science Daily

A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."

From Science Daily

He, like his father, had a genetic disease called osteogenesis imperfecta or brittle bone disease.

From Seattle Times

Ms Moseley-Brown has osteogenesis imperfecta, more commonly known as brittle bone disease.

From BBC