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nalidixic acid
[ ney-li-dik-sik, ney- ]
noun
, Pharmacology.
- a substance, C 1 2 H 1 2 N 2 O 3 , that has antibacterial activity against many susceptible Gram-negative organisms, especially used in the treatment of urinary tract infections.
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Word History and Origins
Origin of nalidixic acid1
1960–65; by shortening and rearrangement of naphthyridine and carboxylic acid, components of its chemical name
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Example Sentences
However, 50 percent of infections resistant to the fluoroquinolone drug nalidixic acid were caused by Salmonella enteritidis, the most common salmonella type.
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Resistance to nalidixic acid -- used in laboratory testing for resistance -- is related to decreased susceptibility to a widely used fluoroquinolone drug ciprofloxacin, the CDC said in its release.
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