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metallo-
- a combining form representing metal in compound words:
metallography.
metallo-
combining_form
- denoting metal
metallography
metallurgy
metalloid
Word History and Origins
Origin of metallo-1
Word History and Origins
Origin of metallo-1
Example Sentences
"Fat is a major component of our diet, and eating trans fats is known to drive heart disease. We used this phenomenon to understand the biological mechanisms putting us at risk," says senior author Christian Metallo, professor and holder of the Daniel and Martina Lewis Chair at Salk.
The fate of dietary fat is often determined by the protein that metabolizes it, explains Metallo, so it was important for the Salk team to first explore the metabolic landscape that creates sphingolipids in the first place.
"We found the incorporation of trans fats through SPT increased lipoprotein secretion from the liver, which then promoted the formation of atherosclerotic plaques," says first author Jivani Gengatharan, a postdoctoral researcher in Metallo's lab.
"As we get a better grasp on identifying and measuring these diverse circulating molecules in our bodies and how they're metabolized, we could make huge strides in personalizing medicine accordingly," says Metallo.
"Our results reveal new therapeutic possibilities for immunotherapy-resistant EGFR-driven lung adenocarcinomas," says co-corresponding author Christian Metallo, professor and holder of the Daniel and Martina Lewis Chair at Salk.
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