kinase

[ kahy-neys, -neyz, kin-eys, -eyz ]

noun

, Biochemistry.

1. a transferase that catalyzes the phosphorylation of a substrate by ATP.

kinase

/ ˈkɪn-; ˈkaɪneɪz /

noun

1. any enzyme that can convert an inactive zymogen to the corresponding enzyme
2. any enzyme that brings about the phosphorylation of a molecule

kinase

/ kī′nās′,-nāz′,kĭn′ās′,-āz′ /

1. Any of various enzymes that catalyze the transfer of a phosphate group from a donor, such as ADP or ATP, to an acceptor.

Word History and Origins

Origin of kinase¹

First recorded in 1900–05; kin(etic) + -ase

Word History and Origins

Origin of kinase¹

C20: from kin ( etic ) + -ase

Example Sentences

Alteration in kinases, which modify many other molecules, have been implicated in driving many cancers.

From Science Daily

"Our group and others have used this approach before to uncover potent and selective kinase inhibitors."

From Science Daily

The team used a combination of laboratory experiments and computational modeling to zero in on how the molecule that serves as a sugar proxy binds to a "sensor kinase" known as KIN10.

From Science Daily

Through another series of experiments, the team linked an increase in activity of so-called stress activated protein kinases to the small percentage of cells that skirt the quiet stage and continue to double their genome.

From Science Daily

Enzymes called DNA damage response kinases and tubulin acetyltransferase are the master regulators of the process, and promote the formation of the tubules.

From Science Daily