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IL-1
Example Sentences
Blocking IL-1 receptors stopped the inflammatory airway secretion from switching on genes for mucins and further inflammatory mediators in cells with cystic fibrosis mutations.
Other drugs that quell IL-6 activity have shown promising results, as has Kineret, a drug that quiets a different cytokine called IL-1.
Other drugs that target the immune system are also being tested, including one called anakinra, which targets a signalling protein called IL-1, and may provide a way to reduce specific immune responses without hampering CD4 and CD8 T cells, says Chen.
Alberto Mantovani and colleagues show in this study that IL-1R8, a negative regulator of the IL-1 family of cytokines, restrains the activity of NK cells.
Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family.
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