IgE

Immunology.

1. immunoglobulin E: a class of antibodies most abundant in tissue spaces, involved in the expulsion of intestinal parasites and causing allergic reactions by activating the release of histamines and leukotrienes in response to certain foreign antigens.

Word History and Origins

Origin of IgE¹

First recorded in 1960–65

Example Sentences

"Mast cells pack a punch, when activated by IgE antibodies they can be said to explode and release inflammatory factors into the skin -- this is what causes itching and hives."

From Science Daily

Food allergy symptoms that are not mediated by IgE are usually delayed reactions and called food intolerances or hypersensitivity.

From Salon

Medication doses were set based on each participant's body weight and IgE levels, with injections given once every two or four weeks, depending on the dose needed.

From Science Daily

Researchers further leveraged samples from ALK clinical trials with tablet sublingual immunotherapy which allows for sequencing large amounts of IgE producing B cells.

From Science Daily

“They also had much higher inflammation in their blood markers, and they also had higher IgE levels, an immunoglobulin associated with reactive airway disease, asthma and other breathing problems.”

From Salon