hyperalgesia

[ hahy-per-al-jee-zee-uh, -see-uh ]

noun

1. an exaggerated sense of pain ( hypalgesia ).

Other Words From

• hyper·al·gesic hy·per·al·get·ic [hahy-per-al-, jet, -ik], adjective

Word History and Origins

Origin of hyperalgesia¹

First recorded in 1895–1900; hyper- + algesia

Example Sentences

Many researchers, therefore, have amelioration of hyperalgesia and allodynia foremost in their minds as they hunt for new analgesics.

From Scientific American

He worried she was susceptible to hyperalgesia, a condition in which prolonged opioid use can alter patients’ nerve receptors and actually cause more pain.

From New York Times

Food and Drug Administration sent a letter to drug companies with approved opioid medications, requiring them to conduct post-marketing studies to better assess the risks of opioid side effects including opioid-induced hyperalgesia—an indication of the growing awareness surrounding this issue.

From Scientific American

By far, the most compelling evidence for opioid-induced hyperalgesia comes from animal studies, which have shed light on potential mechanisms.

From Scientific American

“Can you prevent opioid-induced hyperalgesia and the need for high doses by not using opioids continuously? Knowing this would help to avoid the destructive side effects seen with long-term opioid use and enable us to treat opioid patients better than we do now.”

From Scientific American