graft-versus-host disease

[ graft-vur-suhs-hohst, grahft- ]

noun

1. a reaction in which the cells of transplanted tissue immunologically attack the cells of the host organism, occurring especially in bone-marrow transplants.

Word History and Origins

Origin of graft-versus-host disease¹

First recorded in 1970–75

Example Sentences

For the study, Dr. Kenderian and his team developed CAR-MSCs to specifically target a protein linked to a condition called graft-versus-host disease, as well as inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease.

From Science Daily

Graft-versus-host disease occurs when cells from a donor attack the tissues of the person receiving them, typically following a bone marrow or stem cell transplant.

From Science Daily

Self-derived stem cells could avoid the risks of graft-versus-host disease, a common and potentially deadly reaction that occurs when a patient's immune system perceives the transplant as a threat to be attacked.

From Science Daily

Additionally, there were no signs of complications such as graft-versus-host disease.

From Science Daily

For the study, Yang and her team focused on gamma delta T cells, an immune cell known for its ability to target a wide array of cancers -- including solid tumors -- without causing graft-versus-host disease, a common complication in allogeneic cell therapies.

From Science Daily