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flagellin
/ fləˈdʒɛlɪn /
noun
- the structural protein of bacterial flagella
Example Sentences
The company’s scientists have described a strain of Enterococcus gallinarum, isolated from a healthy human gut, and its structural protein flagellin, which rouses the immune system by interacting with a receptor found on intestinal cells.
Both TLR5 and Reg3γ help to limit early-life colonization by bacteria that express flagellin, which is a component of the flagellar structure that aids bacterial motility.
Flagellin is found on some pathogenic bacteria, although not all bacteria that express flagellin are pathogenic.
In wild-type mice, the intestinal colonization of the strain lacking flagellin was consistently higher than that of the strain that had flagellin.
Fulde et al.1 report that the expression of the protein TLR5 in gut cells during a limited time window in early postnatal development in mice helps to reduce the presence of bacteria that express the protein flagellin.
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