first-line
Americanadjective
-
available for immediate service, especially combat service.
first-line troops.
-
of prime importance or quality.
adjective
Etymology
Origin of first-line
First recorded in 1895–1900
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
For over 60 years, metformin has been a first-line treatment for type 2 diabetes, yet scientists have not fully understood how it works.
From Science Daily • Mar. 25, 2026
This was the first of two late-stage studies for giredestrant as a first-line treatment, Roche said.
From The Wall Street Journal • Mar. 9, 2026
Ms Edwards said the 10 companies in attendance at Thursday's meeting covered a "cross section" of first-line direct suppliers, covering the "whole eco-system" of the supply chain.
From BBC • Sep. 26, 2025
Police also used a liquid known as Bluestar that is meant to be a first-line method of picking up blood stains not visible to the human eye.
From Los Angeles Times • Jun. 1, 2024
A culture showed that the bacilli from his body were resistant to all four of the drugs he’d been given, and to one other first-line antibiotic as well.
From "Mountains Beyond Mountains" by Tracy Kidder and Michael French
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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.