exome

[ ek-sohm ]

noun

1. Genetics. the portions of a gene or genome that code information for protein synthesis; the exons in the human genome.

Word History and Origins

Origin of exome¹

ex(on) ² + (gen)ome

Example Sentences

Researchers provide AIM with patients' exome sequence data and symptoms, and AIM provides a ranking of the most likely gene candidates causing the rare disease.

From Science Daily

The researchers tested AIM's clinical exome reanalysis on a dataset of UDN and DDD cases and found that it was able to correctly identify 57% of diagnosable cases.

From Science Daily

Researchers created and analyzed a database of variants derived from exome sequencing, a genomics assay providing a glimpse into genetic variation genomewide, of 773 unrelated volunteers who were affected with various suspected rare Mendelian disease traits, which are diseases caused by a mutation in a single gene and clearly passed down from one generation to the next in accordance with Gregor Mendel expectations.

From Science Daily

In a new study, recently published in Genetics in Medicine, they show for the first time that using exome sequencing -- which reads only protein-coding DNA -- is as accurate, if not better, than standard microarrays at identifying disease-causing structural genetic variations.

From Science Daily

In this new study, scientists set out to develop a single approach to detect these structural changes, using data available from genome-wide exome sequencing assays.

From Science Daily