estradiol

[ es-truh-dahy-awl, -ol ]

noun

1. Biochemistry. an estrogenic hormone, C 18 H 24 O 2 , produced by the maturing Graafian follicle, that causes proliferation and thickening of the tissues and blood vessels of the endometrium.
2. Pharmacology. a commercial form of this compound, obtained from the urine of pregnant humans and mares or synthesized, used in the treatment of estrogen deficiency and certain menopausal and postmenopausal conditions.

estradiol

/ ˌɛstrəˈdaɪɒl; ˌiːstrə- /

noun

1. the US spelling of oestradiol

Word History and Origins

Origin of estradiol¹

1930–35; estra- (combining form representing estrin ) + di- ¹ + -ol ¹

Example Sentences

When the couple’s older child was 19, living at home as a college student, Mrs. James got a call from the pharmacy informing her that her child’s prescription for estradiol, or estrogen, was ready.

From New York Times

The researchers engineered the yeast to degrade proteins essential for life unless estradiol, a type of oestrogen, was present.

From Science Daily

In addition, women who showed higher levels of phthalates had lower estradiol and higher follicle-stimulating hormone across the menstrual cycle, which play an important role in ovulation and the early establishment of pregnancy.

From Science Daily

So she and her colleagues began collecting urine samples from the primates and testing them for hormonal changes, such as increases in luteinizing hormone and decreases in estradiol, that indicate menopause in humans.

From Scientific American

The research indicates a need to better understand the role of estradiol -- a form of the female sex hormone estrogen, used therapeutically to mitigate menopause symptoms -- in Alzheimer's disease.

From Science Daily