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ergosterol

[ ur-gos-tuh-rohl, -rawl ]

noun

, Biochemistry.
  1. a colorless, crystalline, water-insoluble sterol, C 28 H 43 OH, that occurs in ergot and yeast and that, when irradiated with ultraviolet light, is converted to vitamin D.


ergosterol

/ ɜːˈɡɒstəˌrɒl /

noun

  1. a plant sterol that is converted into vitamin D by the action of ultraviolet radiation. Formula: C 28 H 43 OH
“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word History and Origins

Origin of ergosterol1

First recorded in 1885–90; ergo- 2 + sterol
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Example Sentences

Azoles deplete ergosterol, which results in killing of the pathogen cell.

Together, the teams uncovered the mechanism of the drug: AmB kills fungi by acting like a sponge to extract ergosterol from fungal cells.

They found that AmBMU’s lower potency wasn’t so much because of a looser binding between it and ergosterol, but the slower pace at which the molecule stripped out the membrane component.

Other eukaryotes—organisms with complex cells—produce their own sterols, including stigmasterol in plants and ergosterol in fungi.

Further experiments revealed the pathogens were releasing less of a molecule called ergosterol, which made them visible to the ants.

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