efavirenz

[ uh-fah-vi-renz ]

noun

, Pharmacology.

1. a nonnucleoside reverse transcriptase inhibitor used with other medications to treat HIV infection in patients who have or do not have AIDS.

Word History and Origins

Origin of efavirenz¹

First recorded in 1950–55; shortening of e(thyne) ( def ) + f(luoro-) ( def ) + vir(us) ( def ) + (b)enz(yl) ( def )

Example Sentences

After determining that older mice had more CYP46A1 in their inner ears than younger mice, and therefore had less cholesterol, the researchers used an HIV drug called efavirenz to induce hearing loss in mice.

From Salon

The third group used the standard of care in South Africa, which is tenofovir, FTC, and efavirenz.

From Science Magazine

Between 2012 and 2018, about one-half of newly diagnosed infants in nine of the countries in this region had a form of HIV that was resistant to efavirenz, nevirapine or both.

From Scientific American

In the past 4 years, 12 countries in Africa, Asia and the Americas have surpassed acceptable levels of drug resistance against efavirenz and nevirapine — two drugs that constitute the backbone of HIV treatment.

From Nature

Between 2012 and 2018, about one-half of newly diagnosed infants in nine of the countries in this region had a form of HIV that was resistant to efavirenz, nevirapine or both.

From Nature