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Synonyms

difficile

American  
[dif-i-seel, dee-fee-seel] / ˌdɪf ɪˈsil, di fiˈsil /

adjective

  1. hard to deal with, satisfy, or please.

  2. hard to do; difficult.


Etymology

Origin of difficile

1470–80; < French < Latin difficilis difficult; dif-, facile

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

But scientists noticed hints that faecal transplants for C. difficile also seemed to get rid of superbugs.

From BBC • Jun. 7, 2025

Faecal transplants – also known as a trans-poo-tion - are already approved for treating severe diarrhoea caused by Clostridium difficile bacteria.

From BBC • Jun. 7, 2025

The researchers are currently working on modifying the system to help combat Clostridioides difficile, commonly referred to as C. diff, a bacterium that can cause diarrhea and colitis, among other symptoms.

From Science Daily • Nov. 20, 2024

The drug, called lolamicin, also warded off secondary infections with Clostridioides difficile, a common and dangerous hospital-associated bacterial infection, and was effective against more than 130 multidrug-resistant bacterial strains in cell culture.

From Science Daily • May 29, 2024

Excessive abdominal noise is an uncommon, but not unprecedented, presenting symptom of infection with the bacteria Clostridium difficile, which can be fatal.

From "Turtles All the Way Down" by John Green