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dacarbazine
[ duh-kahr-buh-zeen ]
noun
- a toxic, light-sensitive powder, C 6 H 10 N 6 O, used in the treatment of Hodgkin's disease and metastatic malignant melanoma.
Word History and Origins
Origin of dacarbazine1
Example Sentences
The combinations — Adriamycin, bleomycin, vinblastine and dacarbazine, for instance, to treat Hodgkin’s disease — were rarely changed for individual patients.
Average survival among people who took Halaven was 15.6 months, compared to 8.4 months among those who took another chemotherapy drug, dacarbazine.
Zelboraf led some doctors to question whether to go ahead with the trials they had planned, trials that would pit Zelboraf against the standard treatment, a chemotherapy developed in 1975 called dacarbazine.
Although it is unclear how researchers would predict effective combinations of therapy for certain tumours, recent clinical success of immunotherapy–chemotherapy combinations, for example ipilimumab with dacarbazine for the treatment of metastatic melanoma and vaccination with docetaxel for metastatic androgen-resistant prostate cancer, should force the further consideration of chemotherapy and immunotherapy combinations.
The results from an abstract, or brief summary, of the study showed that Zelboraf led to a median overall survival of 13.2 months compared with 9.6 months for those who received dacarbazine chemotherapy.
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