cytokine

American  

[sahy-tuh-kahyn] / ˈsaɪ təˌkaɪn /

noun

1. a type of small protein, as interferon, secreted by certain cells, especially immune cells, that helps regulate the body’s immune response to inflammation and disease: The largest group of cytokines that stimulate immune cell proliferation are the interleukins.

   Cytokines are like the body’s messenger system for mobilizing its response to pathogens.

   The largest group of cytokines that stimulate immune cell proliferation are the interleukins.

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cytokine British  

/ ˈsaɪtəʊˌkaɪn /

noun

1. any of various proteins, secreted by cells, that carry signals to neighbouring cells. Cytokines include interferon

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cytokine Scientific  

/ sī′tə-kīn′ /

1. Any of several regulatory proteins, such as the interleukins and lymphokines, that are released by cells of the immune system and act as intercellular mediators in the generation of an immune response.

2. Also called chemokine

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Usage

What is a cytokine? A cytokine is a type of protein released by cells in the body to carry messages to other cells. These messages tell the cells to do something, like to start an immune response.Cytokines get triggered by the presence of an antigen, which is any substance, such as a bacterium or virus, that causes the body to produce antibodies.There are many different types of cytokines. Common types are interleukins and lymphokines, which include the cytokines known as interferons.Cytokines play an important role in many different processes, including the regulation of inflammation and the immune response. Sometimes, though, too many cytokines get released. This is known as a cytokine storm, and it makes the body attack itself, resulting in potentially deadly damage to healthy tissue.

Etymology

Origin of cytokine

First recorded in 1970–75; cyto- ( def. ) + -kine, from Greek kineîn “to move, set in motion”; -kinin ( def. )

Example Sentences

Mice receiving arginine also performed better in behavioral assessments and showed decreased expression of pro-inflammatory cytokine genes linked to neuroinflammation, a key contributor to AD progression.

From Science Daily • Nov. 21, 2025

"Another important inflammatory cytokine, TNF-α, was only increased in the younger group," says the researcher.

From Science Daily • Oct. 14, 2025

Conversely, when researchers injected the rats with a substance that agitates the immune system, the inflammatory cytokine levels rapidly shot up.

From Science Daily • Dec. 5, 2024

They discovered that disruption of the internal clock in the epithelial cells lining the intestine alters secretion of cytokine proteins, leading to heightened inflammation, increased numbers of immunosuppressive myeloid cells and cancer progression.

From Science Daily • May 28, 2024

Geneticist Hua Bai of Iowa State University and colleagues discovered that as fruit flies get older, their equivalent of the liver releases more of an inflammation-promoting immune molecule known as a cytokine.

From Science Magazine • May 22, 2024