blast off

1. Become excited or high, especially from using drugs, as in They give parties where people blast off . [ Slang ; c. 1960]

2. Depart, clear out, as in This party's over; let's blast off now . [ Slang ; early 1950s]

3. Also, blast away . Take off or be launched, especially into space, as in They're scheduled to blast off on Tuesday . This usage originated with the development of powerful rockets, spacecraft, and astronauts, to all of which it was applied. [c. 1950]