auranofin

[ aw-ran-uh-fin ]

noun

, Pharmacology.

1. a gold-containing compound, C 20 H 34 AuO 9 PS, used orally in the treatment of rheumatoid arthritis.

Word History and Origins

Origin of auranofin¹

Coinage apparently based on aurum; following syllables unexplained

Example Sentences

Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis.

From Nature

Because auranofin has already been approved for use in humans, we can save years of expensive development.

From BBC

"Although auranofin has to date only been tested in animal models of amoebic disease, this means that there is now a potential alternative treatment for individual cases where metronidazole fails to cure the infection or in the event resistance to metronidazole emerge as a clinical problem in the future."

From BBC

It showed that auranofin was much better than the current treatment, metronidazole, at killing Entamoeba histolytica.

From BBC

The work presented in this paper is particularly useful as it identifies an existing drug, auranofin, that has already been tested and approved for use in humans, which seems to be at least as effective as metronidazole.

From BBC