amitriptyline

[ am-i-trip-tuh-leen, -lahyn, -lin ]

noun

, Pharmacology.

1. a white crystalline powder, C 20 H 23 N, used to treat depression and enuresis.

amitriptyline

/ ˌæmɪˈtrɪptɪˌliːn; -lɪn /

noun

1. a tricyclic antidepressant drug. Formula: C 20 H 23 N

Word History and Origins

Origin of amitriptyline¹

Perhaps ami(no)- + trypt(ophan) + (meth)yl + -ine ²

Word History and Origins

Origin of amitriptyline¹

C20: from amino + tryptamine + methyl + -ine ²

Example Sentences

No safety concerns were identified and side effects in people on amitriptyline were mostly mild, such as a dry mouth in the morning.

From Science Daily

Among the drugs studied - which included Prozac and a cheap antidepressant called amitriptyline - only one, called duloxetine, showed any evidence for pain relief.

From BBC

The researchers randomized the children into three groups that received a placebo, the antidepressant amitriptyline or the antiepileptic medication topiramate.

From Nature

The 500 test patients will be given either amitriptyline or a placebo tablet for six months and their symptoms and mood checked regularly.

From BBC

Mr Saffery, a former youth rugby player for London Irish, was diagnosed with depression in January 2018 and was prescribed amitriptyline.

From BBC