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xenograft
[ zen-uh-graft, -grahft, zee-nuh- ]
noun
- a graft obtained from a member of one species and transplanted to a member of another species.
xenograft
/ ˈzɛnəʊˌɡrɑːft /
xenograft
/ zĕn′ə-grăft′,zē′nə- /
- A graft in which the donor and recipient are of different species.
- Compare allograft
Word History and Origins
Origin of xenograft1
Example Sentences
"This study demonstrated that multiomics can be used to reveal a broad picture of what is happening in the recipient of a xenograft," said Brendan Keating, PhD, a co-senior author on both studies and faculty in Department of Surgery at NYU Grossman School of Medicine.
However, a few parameters, such as establishment of separation technologies at the pharmaceutical level, assessing production process control parameters, and evaluation of efficacy and safety in human cancer cell lines and xenograft animal models, must be investigated prior to clinical trials in humans.
It remains to be seen which cluster of gene edits makes for the best xenograft—or even which ones are necessary.
She injected them into zebrafish embryos, creating xenograft models -- an avatar for each specific patient.
And although xenograft mice from these lines could be valuable, researchers have had more success in skipping the cell-line step to make PDX mice directly.
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