splenomegaly

[ splee-nuh-meg-uh-lee, splen-uh- ]

noun

, Pathology.

1. enlargement of the spleen.

splenomegaly

/ ˌspliːnəʊˈmɛɡəlɪ /

noun

1. pathol abnormal enlargement of the spleen

Word History and Origins

Origin of splenomegaly¹

First recorded in 1895–1900; spleno- + -megaly

Word History and Origins

Origin of splenomegaly¹

C20: from Greek splēno- , from splēn spleen + megalo- , from megas large + -y ³

Example Sentences

Mice in which there was a complete ablation of C9orf72 in all tissues developed and aged normally without the occurrence of motor neuron disease; however, they also developed progressive splenomegaly and lymphadenopathy23, 24, 25, 105.

From Nature

From there the bug causes a purulent lesion and then spreads through the blood and lymph nodes to cause all the symptoms this patient had over the past few weeks: fever and chills, nausea, vomiting and diarrhea, chest pain and splenomegaly.

From New York Times

The most common cause of splenomegaly, or an enlarged spleen, in a young healthy woman was mononucleosis.

From New York Times

Splenomegaly is often seen in the so-called liquid tumors — leukemia and certain lymphomas.

From New York Times