insoluble

[ in-sol-yuh-buhl ]

adjective

1. incapable of being dissolved:

   insoluble salts.

2. incapable of being solved or explained:

   an insoluble problem.

insoluble

/ ɪnˈsɒljʊbəl /

adjective

1. incapable of being dissolved; incapable of forming a solution, esp in water
2. incapable of being solved

insoluble

/ ĭn-sŏl′yə-bəl /

1. Not capable of being fully dissolved. Fats and oils are insoluble in water.

Derived Forms

• inˈsolubly, adverb
• inˌsoluˈbility, noun

Other Words From

• in·solu·bili·ty in·solu·ble·ness noun
• in·solu·bly adverb
• semi-in·solu·ble adjective

Word History and Origins

Origin of insoluble¹

1350–1400; < Latin insolūbilis; replacing Middle English insolible < Middle French insoluble < L. See in- ³, soluble

Example Sentences

During normal disease-free aging, there is also an accumulation of insoluble proteins.

From Science Daily

To date, approaches to treatments for Alzheimer's disease have not addressed the contribution of protein insolubility as a general phenomenon, instead focusing on one or two insoluble proteins.

From Science Daily

Buck researchers have recently completed a systematic study in worms that paints an intricate picture of the connections between insoluble proteins in neurodegenerative diseases and aging.

From Science Daily

"Based on our discoveries, targeting insoluble proteins could provide a strategy for the prevention and treatment of a variety of age-related diseases," said Edward Anderton, PhD, a postdoctoral fellow in Gordon Lithgow's lab and co-first author of a study that appears in the May 16 issue of the journal GeroScience.

From Science Daily

The strong link between insoluble proteins promoting normal aging and diseases also builds a case for the bigger picture of how aging and age-related diseases occur.

From Science Daily