spironolactone

[ spahy-ruh-noh-lak-tohn, spahy-roh-, -ron-uh- ]

noun

, Pharmacology.

1. a steroid, C 2 4 H 3 2 O 4 S, used in combination with other drugs as a diuretic and antihypertensive.

spironolactone

/ ˌspaɪrənəʊˈlæktəʊn /

noun

1. a diuretic that increases water loss from the kidneys and is much used to treat oedema in heart and kidney failure

Word History and Origins

Origin of spironolactone¹

1955–60; alteration of spirolactone; spiro- ², lactone

Word History and Origins

Origin of spironolactone¹

C20: from spiro- ² + linking syllable -no- + lactone

Example Sentences

Cooper asked USA Powerlifting for a “therapeutic-use exemption” to take spironolactone, a medicine prescribed to treat her gender dysphoria, “but JayCee was denied because she’s transgender,” Braverman said.

From Seattle Times

Spironolactone, an oral medication that blocks certain hormones in the body, is sometimes recommended for severe hormonal acne in women.

From Seattle Times

I also take several pills each morning to maintain the proper hormonal balance in my body: spironolactone to suppress testosterone and estradiol to increase estrogen.

From Salon

Cooper, who was taking the testosterone-reducing drug spironolactone, continued to compete in contests run by Open Powerlifting, capturing first place in five championship events in 2019.

From Washington Times

A toxicology analysis turned up positive for the diuretic spironolactone — commonly known by its brand name, Aldactone — and metformin, a diabetes medication that bodybuilders use for weight loss.

From Washington Post