thiazide

[ thahy-uh-zahyd, -zid ]

noun

, Pharmacology.

1. a member of a class of diuretic substances that inhibit the reabsorption of sodium chloride in the distal convoluted tubule of the kidneys: used principally to treat hypertension.

thiazide

/ thī′ə-zīd′,-zĭd /

1. Any of a group of drugs that block reabsorption of sodium in the kidneys, used as diuretics primarily in the treatment of hypertension.

Word History and Origins

Origin of thiazide¹

First recorded in 1955–60; thi- + azide

Example Sentences

Many blood pressure pills such as thiazide diuretics deplete the body of potassium.

From Seattle Times

The all-VUMC team of researchers plans to investigate the underlying mechanisms by which thiazide diuretics lower the risk of kidney stones next.

From Science Daily

Taking a thiazide diuretic, however, had essentially no effect on risk for mood-disorder hospitalization.

From Washington Post

Dr. Riley and Dr. Bluhm listed thiazide diuretics, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, beta blockers and calcium channel blockers as “safe, effective and well-tolerated in children.”

From New York Times

Until recently, the standard advice for most people was to start with a “water pill,” a thiazide diuretic such as hydrochlorothiazide, either alone or with another drug.

From Washington Post