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stop codon

American  

noun

Genetics.
  1. a codon that stops the synthesis of a protein molecule.


stop codon Scientific  
/ stŏp /
  1. Any of three codons in a molecule of messenger RNA that do not code for an amino acid and thereby signal the termination of the synthesis of a protein. The three stop codons are UAA, UAG, and UGA, where U is uracil, A is adenine, and G is guanine.

  2. Also called termination codon


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

It treats a particular three letter sequence, typically a stop codon that marks the end of a protein, in two different ways.

From Science Daily • Feb. 28, 2026

"The UAG codon is like a fork in the road, where it can be interpreted either as a stop codon or as a pyrrolysine residue," Shalvarjian said.

From Science Daily • Feb. 28, 2026

They swapped out the same stop codon in E. coli, but they added another layer of protection.

From Science Magazine • Oct. 19, 2022

Why is the stop codon necessary for translation?

From Textbooks • Jun. 9, 2022

There is a silent mutation in peptide 3 and peptide 2 has a stop codon due to mutation.

From Textbooks • Jun. 9, 2022