sclerosis

American  

[skli-roh-sis] / sklɪˈroʊ sɪs /

noun

plural

scleroses

1. Pathology. a hardening or induration of a tissue or part, or an increase of connective tissue or the like at the expense of more active tissue.

2. Botany. a hardening of a tissue or cell wall by thickening or lignification.

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sclerosis British  

/ sklɪəˈrəʊsɪs /

noun

1. pathol a hardening or thickening of organs, tissues, or vessels from chronic inflammation, abnormal growth of fibrous tissue, or degeneration of the myelin sheath of nerve fibres, or (esp on the inner walls of arteries) deposition of fatty plaques Compare arteriosclerosis atherosclerosis multiple sclerosis

2. the hardening of a plant cell wall or tissue by the deposition of lignin

3. a debilitating lack of progress or innovation within an institution or organization

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Other Word Forms

• sclerosal adjective

Etymology

Origin of sclerosis

1350–1400; Middle English < Medieval Latin < Greek sklḗrōsis hardening. See scler-, -osis

Example Sentences

Its aging multiple sclerosis franchise continues to suffer losses that must be offset by newer drugs.

From Barron's

Nicola King, who was diagnosed with multiple sclerosis at the age of 31, said the sessions meant "everything".

From BBC

His lawyers said he was being treated in the Swiss city of Geneva for multiple sclerosis and condemned the trial as a farce.

From BBC

When Nina Sparks was diagnosed with multiple sclerosis in 2021, she decided very quickly it was going to be the making of her.

From BBC

With fenebrutinib, the company aims to launch a new oral treatment for multiple sclerosis that offers both greater convenience to patients relative to Ocrevus.

From The Wall Street Journal