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neuropeptide

American  
[noor-oh-pep-tahyd, nyoor-] / ˌnʊər oʊˈpɛp taɪd, ˌnyʊər- /

noun

  1. any of various short-chain peptides, as endorphins, that function as neuromodulators in the nervous system and as hormones in the endocrine system.


neuropeptide British  
/ ˌnjʊərəʊˈpɛptaɪd /

noun

  1. a peptide produced by neural tissue, esp one with hormonal activity

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of neuropeptide

First recorded in 1970–75; neuro- + peptide

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

And could the effect of these be boosted by doses of the chemical messenger oxytocin, a neuropeptide that helps affectionate interactions make us feel better physically and emotionally?

From The Wall Street Journal • Dec. 4, 2025

This circuit consists of specialized neurons that send and receive a neuropeptide -- a small protein that sends messages throughout the brain -- called PACAP.

From Science Daily • Jan. 4, 2024

Other researchers, however, express more skepticism about neuropeptide Y’s significance in human evolution.

From Scientific American • Sep. 11, 2023

Exercise, by up-regulating neuropeptide Y, helps soothe the anxious amygdala, dial down the fear and hyper-vigilance and keep us calmer.

From New York Times • Mar. 30, 2022

A neuropeptide is a neurotransmitter molecule made up of chains of amino acids connected by peptide bonds.

From Textbooks • Jun. 19, 2013