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parabiosis

[ par-uh-bahy-oh-sis, -bee- ]

noun

, Biology.
  1. experimental or natural union of two individuals with exchange of blood.
  2. Physiology. the temporary loss of conductivity or excitability of a nerve cell.


parabiosis

/ ˌpærəbaɪˈəʊsɪs; ˌpærəbaɪˈɒtɪk /

noun

  1. the natural union of two individuals, such as Siamese twins, so that they share a common circulation of the blood
  2. a similar union induced for experimental or therapeutic purposes
“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Derived Forms

  • parabiotic, adjective
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Other Words From

  • par·a·bi·ot·ic [par-, uh, -bahy-, ot, -ik, -bee-], adjective
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Word History and Origins

Origin of parabiosis1

First recorded in 1905–10; para- 1 + -biosis
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Word History and Origins

Origin of parabiosis1

C20: from para- 1+ Greek biōsis manner of life, from bios life
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Example Sentences

Several years ago, scientists studying aging at the Harvard Stem Cell Institute used a somewhat Frankensteinian technique known as parabiosis — surgically joining a young mouse and an old mouse so that they share blood — to see what would happen to the heart and skeletal muscle tissue.

It was co-founded in 2018 by Amy Wagers, who was on the Stanford parabiosis revival team and is now a professor of stem-cell and regenerative biology at Harvard University.

Which approach is likely to best slow or reverse age-related diseases based on parabiosis’s effects?

Ambrosia’s approach irks many scientists trying to methodically translate the effects of parabiosis into therapies to slow or reverse ageing.

Studies published in 2013 and 2014 by Wagers’s laboratory and those of the company’s other scientific co-founders, showed that old mice injected with GDF11 reproduced several of the parabiosis findings – with regeneration seen in the heart, skeletal muscle and brain.

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