p53 gene

Cultural  

1. A gene that is thought to play a role in regulating cell death or apoptosis, in suppressing tumors, in regulating the cell cycle, and in stopping the cell from dividing when the DNA is damaged.

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Example Sentences

In around 30 percent of all cases of breast cancer, the cancer cells show mutations or losses in the p53 gene.

From Science Daily • Jan. 3, 2024

Other large animals don't have multiple copies of the p53 gene.

From Scientific American • Jul. 5, 2023

What would be the result of a mutation in the p53 gene that inactivates it?

From Textbooks • Jun. 9, 2022

Researchers tried gene therapy, adding good copies of the p53 gene to cancer cells.

From New York Times • Dec. 22, 2012

For instance, drugs that mimic the action of a normal p53 gene could conceivably cause cancers to revert to a premalignant phase.

From Time Magazine Archive