Hurler syndrome

American  

[hur-ler sin-drohm, -druhm] / ˈhɜr lər ˌsɪn droʊm, -drəm /

Also Hurler's syndrome

noun

Pathology.

1. a congenital abnormality characterized chiefly by dwarfism, deformities of the head, trunk, and limbs, intellectual disability, and enlargement of the liver and spleen.

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Etymology

Origin of Hurler syndrome

First recorded in 1935–40; named after Gertrud Hurler, a German pediatrician who described the disorder in 1919

Example Sentences

There are similar treatments on trial in Manchester for MPS type 1 or Hurler syndrome and MPS type 3 or Sanfilippo syndrome.

From BBC • Nov. 23, 2025

Preliminary results in mice appear encouraging for rare conditions like hemophilia B, Hurler syndrome, Fabry disease and Wolman disease.

From Washington Post • Feb. 5, 2022

The proposal would require the Department of Health and Environmental Control to test for Hurler syndrome, Krabbe and Pompe disease in addition to the 53 conditions the agency already screens.

From Washington Times • Mar. 27, 2019