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Synonyms

malignancy

American  
[muh-lig-nuhn-see] / məˈlɪg nən si /
Also malignance

noun

plural

malignancies
  1. the quality or condition of being malignant.

  2. malignant character, behavior, action, or the like.

    the malignancies of war.

  3. a malignant tumor.


malignancy British  
/ məˈlɪɡnənsɪ /

noun

  1. the state or quality of being malignant

  2. pathol a cancerous growth

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

  • nonmalignance noun
  • nonmalignancy noun

Etymology

Origin of malignancy

First recorded in 1595–1605; malign(ant) + -ancy

Vocabulary lists containing malignancy

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

But he sure makes the strongest case for being the most malevolent, influential force there, a malignancy that poisons everything he touches.

From Los Angeles Times • Jan. 29, 2026

Nothing in these stories, translated by Megan McDowell, is quite impossible, yet the shadow of numinous malignancy hangs over everything.

From The Wall Street Journal • Oct. 9, 2025

Not because cancer had been ruled out — it’s possible that the tests might have missed a subtle malignancy, still brewing.

From Salon • May 20, 2025

Using these images, the model was able to identify patterns that predict anatomical site, malignancy, and prognosis across three different use cases in four cohorts.

From Science Daily • May 7, 2024

Ben laughed and the whole class turned around, as if obedient to one of Sister Loretta’s clicks, to witness the removal of a malignancy from the class.

From "The Great Santini" by Pat Conroy