allopurinol

American  

[al-uh-pyoor-uh-nawl, -nol] / ˌæl əˈpyʊər əˌnɔl, -ˌnɒl /

noun

Pharmacology.

1. a substance, C 5 H 4 N 4 O, used primarily in the treatment of chronic gout to decrease the synthesis of uric acid.

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allopurinol British  

/ ˌæləʊˈpjʊərɪˌnɒl /

noun

1. a synthetic drug that reduces blood concentrations of uric acid and is administered orally in the treatment of gout. Formula: C 5 H 4 N 4 O

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Etymology

Origin of allopurinol

1960–65; apparently allo- + purine + -ol ¹

Example Sentences

“It contains a molecule that’s similar to the drug allopurinol, which is used to treat gout,” Alexon says.

From Washington Post • Aug. 15, 2022

It found that patients on Uloric had a 22 percent higher risk of death from any cause and a 34 percent higher risk of heart-related deaths than patients taking allopurinol, a generic alternative.

From Salon • Jul. 2, 2018

But colchicine doesn't deal with the underlying problem, and White was allergic to the most common anti-uric-acid medicine, allopurinol.

From Washington Post • Mar. 7, 2011

Researchers from the University of Dundee said that studies on allopurinol, a generic gout drug, showed it helped people suffering from angina to exercise more and delayed the time until their chest pain started.

From Reuters • Jun. 7, 2010

"What is exciting is that it looks as if allopurinol may work by protecting the heart from oxygen starvation," said Peter Weissberg, medical director of the British Heart Foundation charity, which funded the study.

From Reuters • Jun. 7, 2010