isoniazid

American  

[ahy-suh-nahy-uh-zid] / ˌaɪ səˈnaɪ ə zɪd /

noun

Pharmacology.

1. a white, crystalline, water-soluble solid, C 6 H 7 N 3 O, used in the treatment of tuberculosis.

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isoniazid British  

/ ˌaɪsəʊˈnaɪəzɪd /

noun

1. a soluble colourless crystalline compound used to treat tuberculosis. Formula: C 6 H 7 N 3 O

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Etymology

Origin of isoniazid

First recorded in 1950–55; short for isonicotinic acid hydrazide

Example Sentences

But most importantly, when an effective treatment became available, it was disseminated worldwide, and part of that happened because isoniazid was unpatentable, so costs for producing it and treating people with it remained low.

From Scientific American • Oct. 17, 2023

Instead of subjecting them all to a recommended prevention strategy—a 9-month course of the drug isoniazid—they treated half with the 9-month course and half with a monthlong combination of isoniazid and rifapentine.

From Science Magazine • Mar. 5, 2018

Decades later, differences in the metabolism of isoniazid were shown to be caused by inherited variants in the NAT2 gene, which encodes the N-acetyltransferase 2 enzyme11, 12.

From Nature • Oct. 13, 2015

Notably, since 2005, there have been major disruptions in the supply of the TB drug isoniazid, as well as tuberculin, which is used to diagnose TB infection.

From Washington Post

He found her almost comatose, kept up Burkhardt's precautionary measures, and started additional injections of isoniazid and streptomycin to attack the suspected tuberculous infection.

From Time Magazine Archive