immune system
Americannoun
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The body system in humans and other animals that protects the organism by distinguishing foreign tissue and neutralizing potentially pathogenic organisms or substances. The immune system includes organs such as the skin and mucous membranes, which provide an external barrier to infection, cells involved in the immune response, such as lymphocytes, and cell products such as lymphokines.
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See also autoimmune disease immune response
Etymology
Origin of immune system
First recorded in 1960–65
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
A modified herpes virus is injected into tumors, which causes cancer cells to burst and release flares that activate and train the immune system to attack cancer cells throughout the body.
From The Wall Street Journal • Apr. 14, 2026
The patient's immune system had been "completely replaced" by the donor's, sqaid study co-author Marius Troseid of the University of Oslo.
From Barron's • Apr. 13, 2026
Together, these discoveries suggest that nutrients from both plant and animal sources may work in complementary ways to support the immune system.
From Science Daily • Apr. 10, 2026
Alongside steroids and emollients, there are immunosuppressants; newer drugs which modify the immune system; and phototherapy which uses UV light.
From BBC • Apr. 10, 2026
“Your immune system hasn’t been exposed to a lifetime of common viruses and bacterial infections. It hasn’t had time to get experience with fighting these infections. It hasn’t had time to get strong.”
From "Everything, Everything" by Nicola Yoon
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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.