homeobox

/ hō′mē-ə-bŏks′ /

1. Any of various DNA sequences containing about 180 nucleotides that encode for corresponding sequences of usually 60 amino acids, called homeodomains , found in proteins that bind DNA and regulate gene transcription. Genes containing homeoboxes are found in all eukaryotic genomes and are associated with cell differentiation and bodily segmentation during embryologic development.

Example Sentences

When they created a wound on the back, they found that only one of two lineages of fibroblast — expressing homeobox protein engrailed-1 — was responsible for the formation of most scar tissue.

From Nature

Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia.

From Nature

Four of them, for instance, are 'homeobox' genes associated with development of the spine and legs.

From Nature

Since some genes have more than one homeobox domain, we kept all domains or chose the longest one according to the state of domain conservation.

From Nature

The consensus sequence preference for the ONECUT3 homeobox factor was obtained from ref.

From Nature