factor VIII

American  

noun

1. antihemophilic factor.

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factor VIII British  

noun

1. a protein that participates in the clotting of blood. It is extracted from donated serum and used in the treatment of the commonest type of haemophilia, in which it is absent

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Etymology

Origin of factor VIII

First recorded in 1960–65

Example Sentences

Only 15% of people with haemophilia have haemophilia B. Most have haemophilia A—a genetic disorder caused by a deficiency in a different blood-clotting protein called factor VIII, which is encoded by a different gene.

From Scientific American • Dec. 9, 2022

They cannot carry a large gene, and the gene for factor VIII, needed to treat hemophilia A, is enormous.

From New York Times • Aug. 13, 2018

Of the 13 patients given higher doses, all are off their haemophilia medication a year on and 11 are producing near-normal levels of factor VIII.

From BBC • Dec. 13, 2017

For factor VIII, Fc fusion extends the half-life from a maximum of about 12 hours to about 18 hours.

From Nature • Nov. 25, 2014

The two main forms of the disease are hemophilia A, caused by a lack of clotting factor VIII, and hemophilia B, caused by a lack of clotting factor IX.

From Reuters • Dec. 11, 2011